Preparation of Rotenone Derivatives and in Vitro Analysis of Their Antimalarial, Antileishmanial and Selective Cytotoxic Activities

Six derivatives of the known biopesticide rotenone were prepared by several chemical transformations. Rotenone and its derivatives showed differential in vitro antiparasitic activity and selective cytotoxicity. In general, compounds were more active against Plasmodium falciparum than Leishmania pana...

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Detalles Bibliográficos
Autores principales: Upegui, Yulieth, Gil, Juan F., Quiñones, Wiston, Torres, Fernando, Escobar, Gustavo, Robledo, Sara M., Echeverri, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271323/
https://www.ncbi.nlm.nih.gov/pubmed/25412039
http://dx.doi.org/10.3390/molecules191118911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271323/
https://www.ncbi.nlm.nih.gov/pubmed/25412039
http://dx.doi.org/10.3390/molecules191118911

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