Synthesis and Biological Evaluation of 2-Phenoxyacetamide Analogues, a Novel Class of Potent and Selective Monoamine Oxidase Inhibitors

Monoamine oxidases (EC 1.4.3.4; MAOs), a family of FAD-containing enzymes, is an important target for antidepressant drugs. In this paper, a series of 2-phenoxyacetamide analogues were synthesized, and their inhibitory potency towards monoamine oxidases A (MAO-A) and B (MAO-B) were evaluated using e...

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Detalles Bibliográficos
Autores principales: Shen, Wei, Yu, Shian, Zhang, Jiaming, Jia, Weizheng, Zhu, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271349/
https://www.ncbi.nlm.nih.gov/pubmed/25405283
http://dx.doi.org/10.3390/molecules191118620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271349/
https://www.ncbi.nlm.nih.gov/pubmed/25405283
http://dx.doi.org/10.3390/molecules191118620

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