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Synthesis and Biological Evaluation of 2-Phenoxyacetamide Analogues, a Novel Class of Potent and Selective Monoamine Oxidase Inhibitors

Monoamine oxidases (EC 1.4.3.4; MAOs), a family of FAD-containing enzymes, is an important target for antidepressant drugs. In this paper, a series of 2-phenoxyacetamide analogues were synthesized, and their inhibitory potency towards monoamine oxidases A (MAO-A) and B (MAO-B) were evaluated using e...

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Detalles Bibliográficos
Autores principales:	Shen, Wei, Yu, Shian, Zhang, Jiaming, Jia, Weizheng, Zhu, Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271349/ https://www.ncbi.nlm.nih.gov/pubmed/25405283 http://dx.doi.org/10.3390/molecules191118620

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