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A QSAR, Pharmacokinetic and Toxicological Study of New Artemisinin Compounds with Anticancer Activity

The Density Functional Theory (DFT) method and the 6-31G** basis set were employed to calculate the molecular properties of artemisinin and 20 derivatives with different degrees of cytotoxicity against the human hepatocellular carcinoma HepG2 line. Principal component analysis (PCA) and hierarchical...

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Detalles Bibliográficos
Autores principales:	Vieira, Josinete B., Braga, Francinaldo S., Lobato, Cleison C., Santos, César F., Costa, Josivan S., Bittencourt, José Adolfo H. M., Brasil, Davi S. B., Silva, Jocivânia O., Hage-Melim, Lorane I. S., Macêdo, Williams Jorge C., Carvalho, José Carlos T., Santos, Cleydson Breno R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271355/ https://www.ncbi.nlm.nih.gov/pubmed/25061720 http://dx.doi.org/10.3390/molecules190810670

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