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Montmorillonite Clay-Promoted, Solvent-Free Cross-Aldol Condensations under Focused Microwave Irradiation

An environmentally benign, clean and general protocol was developed for the synthesis of aryl and heteroaryl trans-chalcones. This method involved solvent-free reaction conditions under microwave irradiation in the presence of a clay-based catalyst, and afforded the target compounds in good yields a...

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Detalles Bibliográficos
Autores principales: Rocchi, Damiano, González, Juan F., Menéndez, J. Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271373/
https://www.ncbi.nlm.nih.gov/pubmed/24901834
http://dx.doi.org/10.3390/molecules19067317
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author Rocchi, Damiano
González, Juan F.
Menéndez, J. Carlos
author_facet Rocchi, Damiano
González, Juan F.
Menéndez, J. Carlos
author_sort Rocchi, Damiano
collection PubMed
description An environmentally benign, clean and general protocol was developed for the synthesis of aryl and heteroaryl trans-chalcones. This method involved solvent-free reaction conditions under microwave irradiation in the presence of a clay-based catalyst, and afforded the target compounds in good yields and short reaction times. Furthermore, the same conditions allowed the synthesis of symmetrical, diarylmethylene-α,β-unsaturated ketones from aromatic aldehydes and ketones.
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spelling pubmed-62713732018-12-21 Montmorillonite Clay-Promoted, Solvent-Free Cross-Aldol Condensations under Focused Microwave Irradiation Rocchi, Damiano González, Juan F. Menéndez, J. Carlos Molecules Article An environmentally benign, clean and general protocol was developed for the synthesis of aryl and heteroaryl trans-chalcones. This method involved solvent-free reaction conditions under microwave irradiation in the presence of a clay-based catalyst, and afforded the target compounds in good yields and short reaction times. Furthermore, the same conditions allowed the synthesis of symmetrical, diarylmethylene-α,β-unsaturated ketones from aromatic aldehydes and ketones. MDPI 2014-06-04 /pmc/articles/PMC6271373/ /pubmed/24901834 http://dx.doi.org/10.3390/molecules19067317 Text en © 2014 by the authors. licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Rocchi, Damiano
González, Juan F.
Menéndez, J. Carlos
Montmorillonite Clay-Promoted, Solvent-Free Cross-Aldol Condensations under Focused Microwave Irradiation
title Montmorillonite Clay-Promoted, Solvent-Free Cross-Aldol Condensations under Focused Microwave Irradiation
title_full Montmorillonite Clay-Promoted, Solvent-Free Cross-Aldol Condensations under Focused Microwave Irradiation
title_fullStr Montmorillonite Clay-Promoted, Solvent-Free Cross-Aldol Condensations under Focused Microwave Irradiation
title_full_unstemmed Montmorillonite Clay-Promoted, Solvent-Free Cross-Aldol Condensations under Focused Microwave Irradiation
title_short Montmorillonite Clay-Promoted, Solvent-Free Cross-Aldol Condensations under Focused Microwave Irradiation
title_sort montmorillonite clay-promoted, solvent-free cross-aldol condensations under focused microwave irradiation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271373/
https://www.ncbi.nlm.nih.gov/pubmed/24901834
http://dx.doi.org/10.3390/molecules19067317
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