Synthesis, Cytotoxicity and Mechanistic Evaluation of 4-Oxoquinoline-3-carboxamide Derivatives: Finding New Potential Anticancer Drugs

As part of a continuing search for new potential anticancer candidates, we describe the synthesis, cytotoxicity and mechanistic evaluation of a series of 4-oxoquinoline-3-carboxamide derivatives as novel anticancer agents. The inhibitory activity of compounds 10–18 was determined against three cance...

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Detalles Bibliográficos
Autores principales: Forezi, Luana da S. M., Tolentino, Nathalia M. C., de Souza, Alessandra M. T., Castro, Helena C., Montenegro, Raquel C., Dantas, Rafael F., Oliveira, Maria E. I. M., Silva, Floriano P., Barreto, Leilane H., Burbano, Rommel M. R., Abrahim-Vieira, Bárbara, de Oliveira, Riethe, Ferreira, Vitor F., Cunha, Anna C., Boechat, Fernanda da C. S., de Souza, Maria Cecília B. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271384/
https://www.ncbi.nlm.nih.gov/pubmed/24858098
http://dx.doi.org/10.3390/molecules19056651

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