Maslinic Acid Induces Mitochondrial Apoptosis and Suppresses HIF-1α Expression in A549 Lung Cancer Cells under Normoxic and Hypoxic Conditions

The apoptotic effects of maslinic acid (MA) at 4, 8, 16, 32 and 64 μmol/L on human lung cancer A549 cells under normoxic and hypoxic conditions were examined. MA at 4–64 and 16–64 μmol/L lowered Bcl-2 expression under normoxic and hypoxic conditions, respectively (p < 0.05). This agent at 4–64 μm...

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Detalles Bibliográficos
Autores principales: Hsia, Te-Chun, Liu, Wen-Hu, Qiu, Wen-Wei, Luo, Jian, Yin, Mei-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271386/
https://www.ncbi.nlm.nih.gov/pubmed/25460312
http://dx.doi.org/10.3390/molecules191219892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271386/
https://www.ncbi.nlm.nih.gov/pubmed/25460312
http://dx.doi.org/10.3390/molecules191219892

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