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Phosphatidylserine-microbubble targeting-activated microglia/macrophage in inflammation combined with ultrasound for breaking through the blood–brain barrier
BACKGROUND AND PURPOSE: Inflammatory reaction plays a crucial role in cerebral ischemia reperfusion (IR) injury. It has been shown that activated microglia long-term existed in cerebral ischemia and induced second injury. Therefore, we hypothesize that prepared phosphatidylserine (PS)-modified micro...
Autores principales: | Zhao, Ranran, Jiang, Jie, Li, Huiwen, Chen, Min, Liu, Renfa, Sun, Sujuan, Ma, De, Liang, Xiaolong, Wang, Shumin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271401/ https://www.ncbi.nlm.nih.gov/pubmed/30501630 http://dx.doi.org/10.1186/s12974-018-1368-1 |
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