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Synthesis and Sar Study of Diarylpentanoid Analogues as New Anti-Inflammatory Agents

A series of ninety-seven diarylpentanoid derivatives were synthesized and evaluated for their anti-inflammatory activity through NO suppression assay using interferone gamma (IFN-γ)/lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages. Twelve compounds (9, 25, 28, 43, 63, 64, 81, 83, 84, 86, 88...

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Detalles Bibliográficos
Autores principales: Leong, Sze Wei, Faudzi, Siti Munirah Mohd, Abas, Faridah, Aluwi, Mohd Fadhlizil Fasihi Mohd, Rullah, Kamal, Wai, Lam Kok, Bahari, Mohd Nazri Abdul, Ahmad, Syahida, Tham, Chau Ling, Shaari, Khozirah, Lajis, Nordin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271425/
https://www.ncbi.nlm.nih.gov/pubmed/25302700
http://dx.doi.org/10.3390/molecules191016058