Design, Synthesis and Biological Evaluation of C(6)-Modified Celastrol Derivatives as Potential Antitumor Agents

New six C6-celastrol derivatives were designed, synthesized, and evaluated for their in vitro cytotoxic activities against nine human cancer cell lines (BGC-823, H4, Bel7402, H522, Colo 205, HepG2 and MDA-MB-468). The results showed that most of the compounds displayed potent inhibition against BGC8...

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Detalles Bibliográficos
Autores principales: Tang, Kaiyong, Huang, Qingqing, Zeng, Jafeng, Wu, Guangming, Huang, Jinwen, Pan, Junfang, Lu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271447/
https://www.ncbi.nlm.nih.gov/pubmed/25025148
http://dx.doi.org/10.3390/molecules190710177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271447/
https://www.ncbi.nlm.nih.gov/pubmed/25025148
http://dx.doi.org/10.3390/molecules190710177

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