Five New Taraxerene-Type Triterpenes from the Branch Barks of Davidia involucrata

Five new taraxerene-type triterpenes, 2-nor-D-friedoolean-14-en-28-ol (1), 2-nor-d-friedoolean-14-en-3α,28-diol (2), 6α-hydroxy-2-nor-D-friedoolean-14-en-3,21-dione (3), 6α,11α,29-trihydroxy-D-friedoolean-14-en-3,16,21-trione (4), and 6α,23,29-trihydroxy-D-friedoolean-14-en-3,16,21-trione (5), were...

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Detalles Bibliográficos
Autores principales: Tan, Qing-Wei, Ouyang, Ming-An, Chen, Qi-Jian, Wu, Zu-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271488/
https://www.ncbi.nlm.nih.gov/pubmed/25361425
http://dx.doi.org/10.3390/molecules191117619
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author Tan, Qing-Wei
Ouyang, Ming-An
Chen, Qi-Jian
Wu, Zu-Jian
author_facet Tan, Qing-Wei
Ouyang, Ming-An
Chen, Qi-Jian
Wu, Zu-Jian
author_sort Tan, Qing-Wei
collection PubMed
description Five new taraxerene-type triterpenes, 2-nor-D-friedoolean-14-en-28-ol (1), 2-nor-d-friedoolean-14-en-3α,28-diol (2), 6α-hydroxy-2-nor-D-friedoolean-14-en-3,21-dione (3), 6α,11α,29-trihydroxy-D-friedoolean-14-en-3,16,21-trione (4), and 6α,23,29-trihydroxy-D-friedoolean-14-en-3,16,21-trione (5), were isolated from the MeOH extract of the branch barks of Davidia involucrata, together with five known compounds. Their structures were elucidated by means of various spectroscopic analyses. Five of the identified compounds showed moderate cytotoxicities against the cell proliferation of SGC-7901, MCF-7, and BEL-7404.
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spelling pubmed-62714882019-01-07 Five New Taraxerene-Type Triterpenes from the Branch Barks of Davidia involucrata Tan, Qing-Wei Ouyang, Ming-An Chen, Qi-Jian Wu, Zu-Jian Molecules Article Five new taraxerene-type triterpenes, 2-nor-D-friedoolean-14-en-28-ol (1), 2-nor-d-friedoolean-14-en-3α,28-diol (2), 6α-hydroxy-2-nor-D-friedoolean-14-en-3,21-dione (3), 6α,11α,29-trihydroxy-D-friedoolean-14-en-3,16,21-trione (4), and 6α,23,29-trihydroxy-D-friedoolean-14-en-3,16,21-trione (5), were isolated from the MeOH extract of the branch barks of Davidia involucrata, together with five known compounds. Their structures were elucidated by means of various spectroscopic analyses. Five of the identified compounds showed moderate cytotoxicities against the cell proliferation of SGC-7901, MCF-7, and BEL-7404. MDPI 2014-10-30 /pmc/articles/PMC6271488/ /pubmed/25361425 http://dx.doi.org/10.3390/molecules191117619 Text en © 2014 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tan, Qing-Wei
Ouyang, Ming-An
Chen, Qi-Jian
Wu, Zu-Jian
Five New Taraxerene-Type Triterpenes from the Branch Barks of Davidia involucrata
title Five New Taraxerene-Type Triterpenes from the Branch Barks of Davidia involucrata
title_full Five New Taraxerene-Type Triterpenes from the Branch Barks of Davidia involucrata
title_fullStr Five New Taraxerene-Type Triterpenes from the Branch Barks of Davidia involucrata
title_full_unstemmed Five New Taraxerene-Type Triterpenes from the Branch Barks of Davidia involucrata
title_short Five New Taraxerene-Type Triterpenes from the Branch Barks of Davidia involucrata
title_sort five new taraxerene-type triterpenes from the branch barks of davidia involucrata
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271488/
https://www.ncbi.nlm.nih.gov/pubmed/25361425
http://dx.doi.org/10.3390/molecules191117619
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