Synthesis and in Vitro Antitumor Activity of a Novel Series of 2-Pyrazoline Derivatives Bearing the 4-Aryloxy-7-chloroquinoline Fragment

A new series of NH-pyrazoline derivatives 6 was synthesized by cyclocondensation reaction of novel [(7-chloroquinolin-4-yl)oxy]chalcones 5 with hydrazine hydrate. The treatment of pyrazolines 6 with acetic anhydride or formic acid yielded the N-acetyl- or N-formylpyrazoline derivatives 7–8, respecti...

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Detalles Bibliográficos
Autores principales: Montoya, Alba, Quiroga, Jairo, Abonia, Rodrigo, Nogueras, Manuel, Cobo, Justo, Insuasty, Braulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271490/
https://www.ncbi.nlm.nih.gov/pubmed/25405285
http://dx.doi.org/10.3390/molecules191118656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271490/
https://www.ncbi.nlm.nih.gov/pubmed/25405285
http://dx.doi.org/10.3390/molecules191118656

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