Cargando…

Conjugates of 1'-Aminoferrocene-1-carboxylic Acid and Proline: Synthesis, Conformational Analysis and Biological Evaluation

Our previous studies showed that alteration of dipeptides Y-Fca-Ala-OMe (III) into Y-Ala-Fca-OMe (IV) (Y = Ac, Boc; Fca = 1'-aminoferrocene-1-carboxylic acid) significantly influenced their conformational space. The novel bioconjugates Y-Fca-Pro-OMe (1, Y = Ac; 2, Y = Boc) and Y-Pro-Fca-OMe (3,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kovačević, Monika, Molčanov, Krešimir, Radošević, Kristina, Srček, Višnja Gaurina, Roca, Sunčica, Čače, Alan, Barišić, Lidija
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271532/ https://www.ncbi.nlm.nih.gov/pubmed/25153883 http://dx.doi.org/10.3390/molecules190812852

Ejemplares similares

Conformational Preferences and Antiproliferative Activity of Peptidomimetics Containing Methyl 1′-Aminoferrocene-1-carboxylate and Turn-Forming Homo- and Heterochiral Pro-Ala Motifs
por: Kovačević, Monika, et al.
Publicado: (2021)

Regio- and enantioselective microbial hydroxylation and evaluation of cytotoxic activity of β-cyclocitral-derived halolactones
por: Mazur, Marcelina, et al.
Publicado: (2017)

Hydrogen Bonding Drives Helical Chirality via 10-Membered Rings in Dipeptide Conjugates of Ferrocene-1,1′-Diamine
por: Kovačević, Monika, et al.
Publicado: (2022)

Agro-Industrial Plant Proteins in Electrospun Materials for Biomedical Application
por: Zdraveva, Emilija, et al.
Publicado: (2023)

Anticancer Aminoferrocene Derivatives Inducing Production of Mitochondrial Reactive Oxygen Species
por: Gizem Özkan, Hülya, et al.
Publicado: (2022)

Novel ferrocene imide derivatives: synthesis, conformational analysis and X-ray structure
por: Semenčić, Mojca Čakić, et al.
Publicado: (2022)

Bioactivity Comparison of Electrospun PCL Mats and Liver Extracellular Matrix as Scaffolds for HepG2 Cells
por: Slivac, Igor, et al.
Publicado: (2021)

2-(4-Aminophenyl)-3,4,5,6-tetrahydropyrimidin-1-ium chloride
por: Molčanov, Krešimir, et al.
Publicado: (2012)

Solid-Phase Synthesis of Amine/Carboxyl Substituted Prolines and Proline Homologues: Scope and Limitations
por: Zhou, Ziniu, et al.
Publicado: (2016)

Preparation of Phosphonic Acid Analogues of Proline and Proline Analogues and Their Biological Evaluation as δ(1)-Pyrroline-5-carboxylate Reductase Inhibitors
por: Qian, Renzhe, et al.
Publicado: (2018)

DNMT3B rs2424913 as a Risk Factor for Congenital Heart Defects in Down Syndrome
por: Majstorović, Dijana, et al.
Publicado: (2023)

Magnetic and Electrical Behaviors of the Homo- and Heterometallic 1D and 3D Coordination Polymers Based on the Partial Decomposition of the [Cr(C(2)O(4))(3)](3−) Building Block
por: Kanižaj, Lidija, et al.
Publicado: (2020)

Photochemical and thermal intramolecular 1,3-dipolar cycloaddition reactions of new o-stilbene-methylene-3-sydnones and their synthesis
por: Butković, Kristina, et al.
Publicado: (2011)

Identification and characterization of trans-3-hydroxy-l-proline dehydratase and Δ(1)-pyrroline-2-carboxylate reductase involved in trans-3-hydroxy-l-proline metabolism of bacteria
por: Watanabe, Seiya, et al.
Publicado: (2014)

Bis[2-(4-aminophenyl)-4,5-dihydro-1H-imidazol-3-ium] dichloride monohydrate
por: Molčanov, Krešimir, et al.
Publicado: (2011)

Mild Copper-Catalyzed, l-Proline-Promoted Cross-Coupling of Methyl 3-Amino-1-benzothiophene-2-carboxylate
por: Kederienė, Vilija, et al.
Publicado: (2021)

Pyrroline-5-carboxylate reductase 1 reprograms proline metabolism to drive breast cancer stemness under psychological stress
por: Cui, Bai, et al.
Publicado: (2023)

A simple and easy to perform synthetic route to functionalized thienyl bicyclo[3.2.1]octadienes
por: Vuk, Dragana, et al.
Publicado: (2020)

Towards understanding π-stacking interactions between non-aromatic rings
por: Molčanov, Krešimir, et al.
Publicado: (2019)

Role of proline and pyrroline-5-carboxylate metabolism in plant defense against invading pathogens
por: Qamar, Aarzoo, et al.
Publicado: (2015)

Assignment of PolyProline II Conformation and Analysis of Sequence – Structure Relationship
por: Mansiaux, Yohann, et al.
Publicado: (2011)

Lysine Acetylation Controls Local Protein Conformation by Influencing Proline Isomerization
por: Howe, Françoise S., et al.
Publicado: (2014)

Proline Residues as Switches in Conformational Changes Leading to Amyloid Fibril Formation
por: Taler-Verčič, Ajda, et al.
Publicado: (2017)

The structure of Medicago truncatula δ(1)-pyrroline-5-carboxylate reductase provides new insights into regulation of proline biosynthesis in plants
por: Ruszkowski, Milosz, et al.
Publicado: (2015)

Tetrakis(2-amino-4-methylpyridinium) cyclo-tetra-μ(2)-oxido-tetrakis[dioxidovanadate(V)] tetrahydrate
por: Tabatabaee, Masoumeh, et al.
Publicado: (2011)

In crystallo screening for proline analog inhibitors of the proline cycle enzyme PYCR1
por: Christensen, Emily M., et al.
Publicado: (2021)

Chemical-Genetic Interactions with the Proline Analog L-Azetidine-2-Carboxylic Acid in Saccharomyces cerevisiae
por: Berg, Matthew D., et al.
Publicado: (2020)

Proline, hydroxyproline, and pyrrolidone carboxylic acid derivatives as highly efficient but reversible transdermal permeation enhancers
por: Kopečná, Monika, et al.
Publicado: (2022)

Proline Dehydrogenase and Pyrroline 5 Carboxylate Dehydrogenase from Mycobacterium tuberculosis: Evidence for Substrate Channeling
por: Kumar, Santosh, et al.
Publicado: (2023)

Fluorocyclopropane-Containing Proline Analogue: Synthesis and Conformation of an Item in the Peptide Chemistʼs Toolbox
por: Pons, Amandine, et al.
Publicado: (2022)

Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling
por: Moseng, Mitchell A., et al.
Publicado: (2022)

Actions of a Proline Analogue, L-Thiazolidine-4-Carboxylic Acid (T4C), on Trypanosoma cruzi
por: Magdaleno, Anahí, et al.
Publicado: (2009)

Appropriate Activity Assays Are Crucial for the Specific Determination of Proline Dehydrogenase and Pyrroline-5-Carboxylate Reductase Activities
por: Lebreton, Sandrine, et al.
Publicado: (2020)

Functional characterization and expression analysis of rice δ(1)-pyrroline-5-carboxylate dehydrogenase provide new insight into the regulation of proline and arginine catabolism
por: Forlani, Giuseppe, et al.
Publicado: (2015)

Conjugation of Carboxylated Graphene Quantum Dots with Cecropin P1 for Bacterial Biosensing Applications
por: Bruce, Jonathan A., et al.
Publicado: (2020)

A Proline-Based Neuraminidase Inhibitor: DFT Studies on the Zwitterion Conformation, Stability and Formation
por: Yang, Zhi-Wei, et al.
Publicado: (2009)

Theoretical and NMR Conformational Studies of β-Proline Oligopeptides With Alternating Chirality of Pyrrolidine Units
por: Mantsyzov, Alexey B., et al.
Publicado: (2018)

Hybrid Cyclobutane/Proline-Containing Peptidomimetics: The Conformational Constraint Influences Their Cell-Penetration Ability
por: Illa, Ona, et al.
Publicado: (2021)

Observation of Distinct Carboxylic Acid Conformers in Aqueous Solution
por: Giubertoni, Giulia, et al.
Publicado: (2019)

Synthesis, crystal structure and spectroscopic and Hirshfeld surface analysis of 4-hydroxy-3-methoxy-5-nitrobenzaldehyde
por: Vusak, Vitomir, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_6dtauu3t1krenr93men8ob57u2