Mechanisms Underlying Vasorelaxation Induced in Rat Aorta by Galetin 3,6-Dimethyl Ether, a Flavonoid from Piptadenia stipulacea (Benth.) Ducke

In this study, we investigated the relaxant action of galetin 3,6-dimethyl ether (FGAL) on rat aorta. The flavonoid relaxed both PMA‑ and phenylephrine (Phe)-induced contractions (pD(2) = 5.36 ± 0.11 and 4.17 ± 0.10, respectively), suggesting the involvement of PKC and Phe pathways or α(1) adrenergi...

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Detalles Bibliográficos
Autores principales: Macêdo, Cibério L., Vasconcelos, Luiz H. C., de C. Correia, Ana C., Martins, Italo R. R., de Lira, Daysianne P., de O. Santos, Bárbara V., de A. Cavalcante, Fabiana, da Silva, Bagnólia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271539/
https://www.ncbi.nlm.nih.gov/pubmed/25438079
http://dx.doi.org/10.3390/molecules191219678

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