Rumphellaones B and C, New 4,5-Seco-Caryophyllane Sesquiterpenoids from Rumphella antipathies

Two new 4,5-seco-caryophyllane sesquiterpenoids, rumphellaones B (1) and C (2), which were found to possess unprecedented γ-lactone moieties, were obtained from the gorgonian coral Rumphella antipathies. The structures of 1 and 2 were elucidated by spectroscopic methods and compound 2 was found to d...

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Autores principales: Chung, Hsu-Ming, Wang, Wei-Hsien, Hwang, Tsong-Long, Li, Jan-Jung, Fang, Lee-Shing, Wu, Yang-Chang, Sung, Ping-Jyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271657/
https://www.ncbi.nlm.nih.gov/pubmed/25153859
http://dx.doi.org/10.3390/molecules190812320
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author Chung, Hsu-Ming
Wang, Wei-Hsien
Hwang, Tsong-Long
Li, Jan-Jung
Fang, Lee-Shing
Wu, Yang-Chang
Sung, Ping-Jyun
author_facet Chung, Hsu-Ming
Wang, Wei-Hsien
Hwang, Tsong-Long
Li, Jan-Jung
Fang, Lee-Shing
Wu, Yang-Chang
Sung, Ping-Jyun
author_sort Chung, Hsu-Ming
collection PubMed
description Two new 4,5-seco-caryophyllane sesquiterpenoids, rumphellaones B (1) and C (2), which were found to possess unprecedented γ-lactone moieties, were obtained from the gorgonian coral Rumphella antipathies. The structures of 1 and 2 were elucidated by spectroscopic methods and compound 2 was found to display modest inhibitory effects on the generation of superoxide anions and the release of elastase by human neutrophils at a concentration of 10 μg/mL.
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spelling pubmed-62716572018-12-27 Rumphellaones B and C, New 4,5-Seco-Caryophyllane Sesquiterpenoids from Rumphella antipathies Chung, Hsu-Ming Wang, Wei-Hsien Hwang, Tsong-Long Li, Jan-Jung Fang, Lee-Shing Wu, Yang-Chang Sung, Ping-Jyun Molecules Article Two new 4,5-seco-caryophyllane sesquiterpenoids, rumphellaones B (1) and C (2), which were found to possess unprecedented γ-lactone moieties, were obtained from the gorgonian coral Rumphella antipathies. The structures of 1 and 2 were elucidated by spectroscopic methods and compound 2 was found to display modest inhibitory effects on the generation of superoxide anions and the release of elastase by human neutrophils at a concentration of 10 μg/mL. MDPI 2014-08-14 /pmc/articles/PMC6271657/ /pubmed/25153859 http://dx.doi.org/10.3390/molecules190812320 Text en © 2014 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Chung, Hsu-Ming
Wang, Wei-Hsien
Hwang, Tsong-Long
Li, Jan-Jung
Fang, Lee-Shing
Wu, Yang-Chang
Sung, Ping-Jyun
Rumphellaones B and C, New 4,5-Seco-Caryophyllane Sesquiterpenoids from Rumphella antipathies
title Rumphellaones B and C, New 4,5-Seco-Caryophyllane Sesquiterpenoids from Rumphella antipathies
title_full Rumphellaones B and C, New 4,5-Seco-Caryophyllane Sesquiterpenoids from Rumphella antipathies
title_fullStr Rumphellaones B and C, New 4,5-Seco-Caryophyllane Sesquiterpenoids from Rumphella antipathies
title_full_unstemmed Rumphellaones B and C, New 4,5-Seco-Caryophyllane Sesquiterpenoids from Rumphella antipathies
title_short Rumphellaones B and C, New 4,5-Seco-Caryophyllane Sesquiterpenoids from Rumphella antipathies
title_sort rumphellaones b and c, new 4,5-seco-caryophyllane sesquiterpenoids from rumphella antipathies
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271657/
https://www.ncbi.nlm.nih.gov/pubmed/25153859
http://dx.doi.org/10.3390/molecules190812320
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