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A New Cycloartane-Type Triterpenoid Saponin Xanthine Oxidase Inhibitor from Homonoia riparia Lour
A new cycloartane-type triterpenoid saponin named riparsaponin (1) was isolated from the stem of Homonoia riparia Lour together with six known compounds. The structure of riparsaponin was determined by using NMR and mass spectroscopy and X-ray crystallography techniques. Additionally, riparsaponin h...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271680/ https://www.ncbi.nlm.nih.gov/pubmed/25178063 http://dx.doi.org/10.3390/molecules190913422 |
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author | Xu, Fan Zhao, Xueqian Yang, Lingli Wang, Xiuhua Zhao, Jing |
author_facet | Xu, Fan Zhao, Xueqian Yang, Lingli Wang, Xiuhua Zhao, Jing |
author_sort | Xu, Fan |
collection | PubMed |
description | A new cycloartane-type triterpenoid saponin named riparsaponin (1) was isolated from the stem of Homonoia riparia Lour together with six known compounds. The structure of riparsaponin was determined by using NMR and mass spectroscopy and X-ray crystallography techniques. Additionally, riparsaponin has a significant inhibitory effect on xanthine oxidase in vitro, and the IC(50) was 11.16 nmol/mL. |
format | Online Article Text |
id | pubmed-6271680 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-62716802018-12-27 A New Cycloartane-Type Triterpenoid Saponin Xanthine Oxidase Inhibitor from Homonoia riparia Lour Xu, Fan Zhao, Xueqian Yang, Lingli Wang, Xiuhua Zhao, Jing Molecules Communication A new cycloartane-type triterpenoid saponin named riparsaponin (1) was isolated from the stem of Homonoia riparia Lour together with six known compounds. The structure of riparsaponin was determined by using NMR and mass spectroscopy and X-ray crystallography techniques. Additionally, riparsaponin has a significant inhibitory effect on xanthine oxidase in vitro, and the IC(50) was 11.16 nmol/mL. MDPI 2014-08-29 /pmc/articles/PMC6271680/ /pubmed/25178063 http://dx.doi.org/10.3390/molecules190913422 Text en © 2014 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Communication Xu, Fan Zhao, Xueqian Yang, Lingli Wang, Xiuhua Zhao, Jing A New Cycloartane-Type Triterpenoid Saponin Xanthine Oxidase Inhibitor from Homonoia riparia Lour |
title | A New Cycloartane-Type Triterpenoid Saponin Xanthine Oxidase Inhibitor from Homonoia riparia Lour |
title_full | A New Cycloartane-Type Triterpenoid Saponin Xanthine Oxidase Inhibitor from Homonoia riparia Lour |
title_fullStr | A New Cycloartane-Type Triterpenoid Saponin Xanthine Oxidase Inhibitor from Homonoia riparia Lour |
title_full_unstemmed | A New Cycloartane-Type Triterpenoid Saponin Xanthine Oxidase Inhibitor from Homonoia riparia Lour |
title_short | A New Cycloartane-Type Triterpenoid Saponin Xanthine Oxidase Inhibitor from Homonoia riparia Lour |
title_sort | new cycloartane-type triterpenoid saponin xanthine oxidase inhibitor from homonoia riparia lour |
topic | Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271680/ https://www.ncbi.nlm.nih.gov/pubmed/25178063 http://dx.doi.org/10.3390/molecules190913422 |
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