Synthesis and Anti-hypertensive Effects of the Twin Drug of Nicotinic Acid and Quercetin Tetramethyl Ether

A novel twin drug consisting of nicotinic acid (VB3) and quercetin tetramethyl ether (QTME) has been synthesized as an antihypertensive in a total yield of 79.2% through methylation, hydrolysis, acylation and esterification starting from rutin. The structures of synthesized compounds were elucidated...

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Detalles Bibliográficos
Autores principales: Wang, Zhonglei, Yang, Liyan, Cui, Shuai, Liang, Yingxi, Zhang, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271710/
https://www.ncbi.nlm.nih.gov/pubmed/24743936
http://dx.doi.org/10.3390/molecules19044791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271710/
https://www.ncbi.nlm.nih.gov/pubmed/24743936
http://dx.doi.org/10.3390/molecules19044791

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