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4-Amino-substituted Benzenesulfonamides as Inhibitors of Human Carbonic Anhydrases

A series of N-aryl-β-alanine derivatives and diazobenzenesulfonamides containing aliphatic rings were designed, synthesized, and their binding to carbonic anhydrases (CA) I, II, VI, VII, XII, and XIII was studied by the fluorescent thermal shift assay and isothermal titration calorimetry. The result...

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Detalles Bibliográficos
Autores principales: Rutkauskas, Kęstutis, Zubrienė, Asta, Tumosienė, Ingrida, Kantminienė, Kristina, Kažemėkaitė, Marytė, Smirnov, Alexey, Kazokaitė, Justina, Morkūnaitė, Vaida, Čapkauskaitė, Edita, Manakova, Elena, Gražulis, Saulius, Beresnevičius, Zigmuntas J., Matulis, Daumantas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271771/
https://www.ncbi.nlm.nih.gov/pubmed/25353386
http://dx.doi.org/10.3390/molecules191117356