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Three-Dimensional Heterocycles: New Uracil-Based Structures Obtained by Nucleophilic Substitution at the sp(2) Carbon of Bromoisoxazoline

The regioisomeric cycloadducts of bromonitrile oxide and N-benzoyl-2,3-oxaza-norborn-5-ene were easily prepared and elaborated into a novel class of uracil-based scaffolds. The key-synthetic step is the nucleophilic substitution at the sp(2) carbon atom of the bromoisoxazoline three-dimensional hete...

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Detalles Bibliográficos
Autores principales:	Memeo, Misal Giuseppe, Lapolla, Francesco, Bovio, Bruna, Quadrelli, Paolo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271772/ https://www.ncbi.nlm.nih.gov/pubmed/24962398 http://dx.doi.org/10.3390/molecules19068661

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