Cargando…

Matrilin-2 Is Proteolytically Cleaved by ADAMTS-4 and ADAMTS-5

Matrilin-2 is a widely distributed, oligomeric extracellular matrix protein that forms a filamentous network by binding to a variety of different extracellular matrix proteins. We found matrilin-2 proteolytic products in transfected cell lines in vitro and in mouse tissues in vivo. Two putative clea...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Zhengke, Luo, Junming, Iwamoto, Satori, Chen, Qian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271824/ https://www.ncbi.nlm.nih.gov/pubmed/24959676 http://dx.doi.org/10.3390/molecules19068472

Ejemplares similares

Regulated Proteolytic Processing of Reelin through Interplay of Tissue Plasminogen Activator (tPA), ADAMTS-4, ADAMTS-5, and Their Modulators
por: Krstic, Dimitrije, et al.
Publicado: (2012)

ADAMTS-9 in Mouse Cartilage Has Aggrecanase Activity That Is Distinct from ADAMTS-4 and ADAMTS-5
por: Rogerson, Fraser M., et al.
Publicado: (2019)

Conformational quiescence of ADAMTS‐13 prevents proteolytic promiscuity
por: South, K., et al.
Publicado: (2016)

ADAMTS-4_v1 Is a Splice Variant of ADAMTS-4 That Is Expressed as a Protein in Human Synovium and Cleaves Aggrecan at the Interglobular Domain
por: Wainwright, Shane D, et al.
Publicado: (2013)

Post-translational regulation and proteolytic activity of the metalloproteinase ADAMTS8
por: Santamaria, Salvatore, et al.
Publicado: (2021)

Proteolytic Processing of Von Willebrand Factor by Adamts13 and Leukocyte Proteases
por: Lancellotti, Stefano, et al.
Publicado: (2013)

Matrilin-3 Induction of IL-1 receptor antagonist Is required for up-regulating collagen II and aggrecan and down-regulating ADAMTS-5 gene expression
por: Jayasuriya, Chathuraka T, et al.
Publicado: (2012)

ADAMTS2 and ADAMTS14 can substitute for ADAMTS3 in adults for pro-VEGFC activation and lymphatic homeostasis
por: Dupont, Laura, et al.
Publicado: (2022)

Cleavage of Fibulin-2 by the aggrecanases ADAMTS-4 and ADAMTS-5 contributes to the tumorigenic potential of breast cancer cells
por: Fontanil, Tania, et al.
Publicado: (2017)

The ADAMTS/Fibrillin Connection: Insights into the Biological Functions of ADAMTS10 and ADAMTS17 and Their Respective Sister Proteases
por: Karoulias, Stylianos Z., et al.
Publicado: (2020)

ADAMTS9, a member of the ADAMTS family, in Xenopus development
por: Desanlis, Ines, et al.
Publicado: (2018)

Association of ADAMTS4 and ADAMTS5 polymorphisms with musculoskeletal degenerative diseases: a systematic review and meta-analysis
por: Huo, Jian-Zhong, et al.
Publicado: (2018)

The emerging roles of ADAMTS-7 and ADAMTS-12 matrix metalloproteinases
por: Lin, Edward A, et al.
Publicado: (2009)

Reactive-site mutants of N-TIMP-3 that selectively inhibit ADAMTS-4 and ADAMTS-5: biological and structural implications
por: Lim, Ngee H., et al.
Publicado: (2010)

Severe Dengue Is Associated with Consumption of von Willebrand Factor and Its Cleaving Enzyme ADAMTS-13
por: Djamiatun, Kis, et al.
Publicado: (2012)

ADAMTS4 and ADAMTS5 Knockout Mice Are Protected from Versican but Not Aggrecan or Brevican Proteolysis during Spinal Cord Injury
por: Demircan, Kadir, et al.
Publicado: (2014)

The Metalloproteinase ADAMTS5 Is Expressed by Interstitial Inflammatory Cells in IgA Nephropathy and Is Proteolytically Active on the Kidney Matrix
por: Taylor, Scott, et al.
Publicado: (2020)

Regulation of ADAMTS Proteases
por: Rose, Keron W. J., et al.
Publicado: (2021)

ADAMTS13 and Non-ADAMTS13 Biomarkers in Immune-Mediated Thrombotic Thrombocytopenic Purpura
por: Bonnez, Quintijn, et al.
Publicado: (2023)

Characterization and regulation of ADAMTS-16
por: Surridge, Alison K, et al.
Publicado: (2009)

ADAMTS13, TTP and Beyond
por: Zheng, X Long
Publicado: (2012)

ADAMTS Expression in Colorectal Cancer
por: Filou, Serafula, et al.
Publicado: (2015)

Mechanisms of ADAMTS13 regulation
por: DeYoung, Veronica, et al.
Publicado: (2022)

Assessing Serum Levels of ADAMTS1 and ADAMTS4 as New Biomarkers for Patients with Type A Acute Aortic Dissection
por: Li, Kui, et al.
Publicado: (2017)

Disappearing acts of ADAMTS13
por: Voorberg, Jan, et al.
Publicado: (2015)

The role of ADAMTS genes in preeclampsia
por: Gökdemir, İrem Eda, et al.
Publicado: (2016)

Hyalectanase Activities by the ADAMTS Metalloproteases
por: Fontanil, Tania, et al.
Publicado: (2021)

Antibody-based exosite inhibitors of ADAMTS-5 (aggrecanase-2)
por: Santamaria, Salvatore, et al.
Publicado: (2015)

Genetic variation of aggrecanase-2 (ADAMTS5) in susceptibility to osteoarthritis
por: Zhou, Xindie, et al.
Publicado: (2019)

Degradomic Identification of Membrane Type 1-Matrix Metalloproteinase as an ADAMTS9 and ADAMTS20 Substrate
por: Nandadasa, Sumeda, et al.
Publicado: (2023)

The ADAMTS5 Metzincin Regulates Zebrafish Somite Differentiation
por: Dancevic, Carolyn M., et al.
Publicado: (2018)

Exosite inhibition of ADAMTS-5 by a glycoconjugated arylsulfonamide
por: Santamaria, Salvatore, et al.
Publicado: (2021)

In vivo N-Terminomics Highlights Novel Functions of ADAMTS2 and ADAMTS14 in Skin Collagen Matrix Building
por: Leduc, Cédric, et al.
Publicado: (2021)

Functional role of ADAMTS5 in adiposity and metabolic health
por: Bauters, Dries, et al.
Publicado: (2018)

ADAMTS Sol narae cleaves extracellular Wingless to generate a novel active form that regulates cell proliferation in Drosophila
por: Won, Jong-Hoon, et al.
Publicado: (2019)

ADAMTS13 Deficiency Worsens Colitis and Exogenous ADAMTS13 Administration Decreases Colitis Severity in Mice
por: Zitomersky, Naamah L., et al.
Publicado: (2017)

Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican
por: Hong, Courtney C., et al.
Publicado: (2020)

Systemic antithrombotic effects of ADAMTS13
por: Chauhan, Anil K., et al.
Publicado: (2006)

The utility of synovial fluid levels of ADAMTS9 and ADAMTS4 in predicting treatment responses to intraarticular steroid injections in patients with knee osteoarthritis
por: ÖZLER, Kenan
Publicado: (2020)

ADAMTS-1 in abdominal aortic aneurysm
por: Vorkapic, Emina, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_fi1u06ctal0g8idl2jn38a5sta