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Synthesis of New Quinoxalines Containing an Oxirane Ring by the TDAE Strategy and in Vitro Evaluation in Neuroblastoma Cell Lines
Neuroblastoma is an aggressive pediatric malignancy with significant chemotherapeutic resistance. In order to obtain new compounds active on neuroblastoma cell lines, we investigated the reactivity of carbanion formed via TDAE in quinoxaline series. The new synthesized compounds were tested for thei...
Autores principales: | Montana, Marc, Correard, Florian, Khoumeri, Omar, Esteve, Marie-Anne, Terme, Thierry, Vanelle, Patrice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271844/ https://www.ncbi.nlm.nih.gov/pubmed/25237753 http://dx.doi.org/10.3390/molecules190914987 |
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