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Synthesis and Cytotoxicity of 2,3-Enopyranosyl C-Linked Conjugates of Genistein

A series of glycoconjugates, derivatives of genistein containing a C-glycosylated carbohydrate moiety, were synthesized and their anticancer activity was tested in vitro in the human cell lines HCT 116 and DU 145. The target compounds 15–17 were synthesized by treating ω-bromoalkyl C-glycosides deri...

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Detalles Bibliográficos
Autores principales: Szeja, Wieslaw, Grynkiewicz, Grzegorz, Bieg, Tadeusz, Swierk, Piotr, Byczek, Anna, Papaj, Katarzyna, Kitel, Radosław, Rusin, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271854/
https://www.ncbi.nlm.nih.gov/pubmed/24886936
http://dx.doi.org/10.3390/molecules19067072