Two New Lanostane Triterpenoids from the Branches and Leaves of Polyalthia oblique

Two new lanostane triterpenoids, 20-hydroxyeuphorbol-7-one (1) and 15α-hydroxyeuphorbol-7,11-dione (2), together with four known triterpenoids, euphorbol-7-one (3), friedelin (4), stigmast-4-ene-6α-ol-3-one (5), stigmasta-4-en-3,6-dione (6), were isolated from ethanol extract of the branches and lea...

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Detalles Bibliográficos
Autores principales: Wang, Liu-Kai, Zheng, Cai-Juan, Li, Xiao-Bao, Chen, Guang-Ying, Han, Chang-Ri, Chen, Wen-Hao, Song, Xiao-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271888/
https://www.ncbi.nlm.nih.gov/pubmed/24914904
http://dx.doi.org/10.3390/molecules19067621
Descripción
Sumario:Two new lanostane triterpenoids, 20-hydroxyeuphorbol-7-one (1) and 15α-hydroxyeuphorbol-7,11-dione (2), together with four known triterpenoids, euphorbol-7-one (3), friedelin (4), stigmast-4-ene-6α-ol-3-one (5), stigmasta-4-en-3,6-dione (6), were isolated from ethanol extract of the branches and leaves of Polyalthia obliqua. The structures of 1 and 2 were elucidated on the basis of extensive spectroscopic analysis and comparisons with related known compounds. Antibacterial activities of two new compounds and four known compounds were tested.

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