Evaluation of the Toxicity of 5-Aryl-2-Aminoimidazole-Based Biofilm Inhibitors against Eukaryotic Cell Lines, Bone Cells and the Nematode Caenorhabditis elegans

Previously, we have synthesized several series of compounds based on the 5-aryl-2-aminoimidazole scaffold, which showed a preventive activity against microbial biofilms. We here studied the cytotoxicity of the most active compounds of each series. First, the cytostatic activity was investigated agai...

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Detalles Bibliográficos
Autores principales: Steenackers, Hans, Dubey, Akanksha, Robijns, Stijn, Ermolat’ev, Denis, Delattin, Nicolas, Dovgan, Barbara, Girandon, Lenart, Fröhlich, Mirjam, De Brucker, Katrijn, Cammue, Bruno P. A., Thevissen, Karin, Balzarini, Jan, Van der Eycken, Erik V., Vanderleyden, Jozef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271933/
https://www.ncbi.nlm.nih.gov/pubmed/25325155
http://dx.doi.org/10.3390/molecules191016707

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