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Anti-Fibrosis Effect of Scutellarin via Inhibition of Endothelial–Mesenchymal Transition on Isoprenaline-Induced Myocardial Fibrosis in Rats
Scutellarin (SCU) is the major active component of breviscapine and has been reported to be capable of decreasing myocardial fibrosis. The aim of the present study is to investigate whether SCU treatment attenuates isoprenaline-induced myocardial fibrosis and the mechanisms of its action. Rats were...
Autores principales: | Zhou, Hao, Chen, Xiao, Chen, Lingzhi, Zhou, Xi, Zheng, Gaoshu, Zhang, Huaiqin, Huang, Weijian, Cai, Jiejie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271942/ https://www.ncbi.nlm.nih.gov/pubmed/25268717 http://dx.doi.org/10.3390/molecules191015611 |
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