Synergism of Cyclin-Dependent Kinase Inhibitors with Camptothecin Derivatives in Small Cell Lung Cancer Cell Lines

Advanced small cell lung cancer (SCLC) has a dismal prognosis. Modulation of the camptothecin topotecan, approved for second-line therapy, may improve response. Our recent finding of synergistic enhancement of the cytotoxic activity of camptothecin (CPT) by cyclin-dependent kinase 4 inhibitors is ex...

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Detalles Bibliográficos
Autores principales: Hamilton, Gerhard, Klameth, Lukas, Rath, Barbara, Thalhammer, Theresia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271949/
https://www.ncbi.nlm.nih.gov/pubmed/24549232
http://dx.doi.org/10.3390/molecules19022077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271949/
https://www.ncbi.nlm.nih.gov/pubmed/24549232
http://dx.doi.org/10.3390/molecules19022077

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