Structure-Activity Relationship Study of Sesquiterpene Lactones and Their Semi-Synthetic Amino Derivatives as Potential Antitrypanosomal Products

Sesquiterpene lactones (STLs) are natural products that have potent antitrypanosomal activity in vitro and, in the case of cynaropicrin, also reduce parasitemia in the murine model of trypanosomiasis. To explore their structure-antitrypanosomal activity relationships, a set of 34 natural and semi-sy...

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Detalles Bibliográficos
Autores principales: Zimmermann, Stefanie, Fouché, Gerda, De Mieri, Maria, Yoshimoto, Yukiko, Usuki, Toyonobu, Nthambeleni, Rudzani, Parkinson, Christopher J., van der Westhuyzen, Christiaan, Kaiser, Marcel, Hamburger, Matthias, Adams, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271975/
https://www.ncbi.nlm.nih.gov/pubmed/24662071
http://dx.doi.org/10.3390/molecules19033523

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