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Bio-Inspired Nitrile Hydration by Peptidic Ligands Based on L-Cysteine, L-Methionine or L-Penicillamine and Pyridine-2,6-dicarboxylic Acid

Nitrile hydratase (NHase, EC 4.2.1.84) is a metalloenzyme which catalyses the conversion of nitriles to amides. The high efficiency and broad substrate range of NHase have led to the successful application of this enzyme as a biocatalyst in the industrial syntheses of acrylamide and nicotinamide and...

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Detalles Bibliográficos
Autores principales: Byrne, Cillian, Houlihan, Kate M., Devi, Prarthana, Jensen, Paul, Rutledge, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271992/
https://www.ncbi.nlm.nih.gov/pubmed/25514220
http://dx.doi.org/10.3390/molecules191220751

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