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Moderate aerobic exercise training decreases middle-aged induced pathologic cardiac hypertrophy by improving Klotho expression, MAPK signaling pathway, and oxidative stress status in Wistar rats

OBJECTIVE(S): This study aimed to investigate the effect of aerobic training on serum levels of Klotho, cardiac tissue levels of H(2)O(2) and phosphorylation of ERK1/2 and P38 as well as left ventricular internal diameter (LVID), the left ventricle wall thickness (LVWT) and fibrosis in middle-aged r...

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Detalles Bibliográficos
Autores principales: Baghaiee, Behrouz, Karimi, Pouran, Siahkouhian, Marefat, Pescatello, Linda S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272071/
https://www.ncbi.nlm.nih.gov/pubmed/30524691