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Phase 1 study of olaratumab plus doxorubicin in Japanese patients with advanced soft‐tissue sarcoma
Olaratumab, a monoclonal antibody targeting human platelet‐derived growth factor receptor α, plus doxorubicin significantly improved overall survival in patients with advanced soft‐tissue sarcoma (STS) in a prior phase 1b/2 randomized trial. Subsequent exposure‐response analysis suggested that highe...
Autores principales: | Yonemori, Kan, Kodaira, Makoto, Satoh, Taroh, Kudo, Toshihiro, Takahashi, Shunji, Nakano, Kenji, Ando, Yuichi, Shimokata, Tomoya, Mori, Joji, Inoue, Koichi, Oakley, Gerard J., Sakaguchi, Sachi, Tamura, Kenji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272083/ https://www.ncbi.nlm.nih.gov/pubmed/30353601 http://dx.doi.org/10.1111/cas.13846 |
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