Exploration of resistance mechanisms for epidermal growth factor receptor‐tyrosine kinase inhibitors based on plasma analysis by digital polymerase chain reaction and next‐generation sequencing

Liquid biopsy offers a potential alternative to tissue biopsy for detection of genetic alterations in cancer, and it has been introduced into clinical practice to detect the tyrosine kinase inhibitor (TKI) resistance‐conferring T790M mutation of epidermal growth factor receptor (EGFR) in patients wi...

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Detalles Bibliográficos
Autores principales: Iwama, Eiji, Sakai, Kazuko, Azuma, Koichi, Harada, Daijiro, Nosaki, Kaname, Hotta, Katsuyuki, Nishio, Makoto, Kurata, Takayasu, Fukuhara, Tatsuro, Akamatsu, Hiroaki, Goto, Koichi, Shimose, Takayuki, Kishimoto, Junji, Nakanishi, Yoichi, Nishio, Kazuto, Okamoto, Isamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272092/
https://www.ncbi.nlm.nih.gov/pubmed/30289575
http://dx.doi.org/10.1111/cas.13820

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