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Pattern and prognostic value of FLT3‐ITD mutations in Chinese de novo adult acute myeloid leukemia

FMS‐like tyrosine kinase 3 (FLT3) is one of the most frequently mutated genes in hematological malignancies. FLT3 internal tandem duplication (FLT3‐ITD) mutations located in juxtamembrane domain (JMD) and tyrosine kinase domain 1 (TKD1) regions account for two‐thirds of all FLT3 mutations. The outco...

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Detalles Bibliográficos
Autores principales: Liu, Song‐Bai, Qiu, Qiao‐Cheng, Bao, Xie‐Bing, Ma, Xiao, Li, Hong‐Zhi, Liu, Yue‐Jun, Chen, Su‐Ning, Song, Yao‐Hua, Wu, De‐Pei, Xue, Sheng‐Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272103/
https://www.ncbi.nlm.nih.gov/pubmed/30320942
http://dx.doi.org/10.1111/cas.13835