Epidermal growth factor receptor promotes glioma progression by regulating xCT and GluN2B‐containing N‐methyl‐d‐aspartate–sensitive glutamate receptor signaling

Autocrine and paracrine factors, including glutamate and epidermal growth factor (EGF), are potent inducers of brain tumor cell invasion, a pathological hallmark of malignant gliomas. System xc(–) consists of xCT and CD98hc subunits and functions as a plasma membrane antiporter for the uptake of ext...

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Detalles Bibliográficos
Autores principales: Suina, Kentaro, Tsuchihashi, Kenji, Yamasaki, Juntaro, Kamenori, Shohei, Shintani, Subaru, Hirata, Yuki, Okazaki, Shogo, Sampetrean, Oltea, Baba, Eishi, Akashi, Koichi, Mitsuishi, Yoichiro, Takahashi, Fumiyuki, Takahashi, Kazuhisa, Saya, Hideyuki, Nagano, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272110/
https://www.ncbi.nlm.nih.gov/pubmed/30298963
http://dx.doi.org/10.1111/cas.13826

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