Fibroblast growth factor receptor 3‐mediated reactivation of ERK signaling promotes head and neck squamous cancer cell insensitivity to MEK inhibition

Recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) has been a longstanding challenge for head and neck oncologists, and current treatments still have limited efficacy. ERK is aberrantly overexpressed and activated in HNSCC. Herein, we aimed to investigate the cause of the limited...

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Detalles Bibliográficos
Autores principales: Ban, Myung Jin, Byeon, Hyung Kwon, Yang, Yeon Ju, An, Sojung, Kim, Jae Wook, Kim, Ji‐Hoon, Kim, Da Hee, Yang, Jaemoon, Kee, Hyunjung, Koh, Yoon Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272115/
https://www.ncbi.nlm.nih.gov/pubmed/30343534
http://dx.doi.org/10.1111/cas.13839

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