Reinforce the antitumor activity of CD8(+) T cells via glutamine restriction

The antitumor activity of activated CD8+ T cells in the tumor microenvironment seems to be limited due to their being metabolically unfit. This metabolic unfitness is closely associated with T‐cell exhaustion and impairment of memory formation, which are barriers to successful antitumor adoptive imm...

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Detalles Bibliográficos
Autores principales: Nabe, Shogo, Yamada, Takeshi, Suzuki, Junpei, Toriyama, Koji, Yasuoka, Toshiaki, Kuwahara, Makoto, Shiraishi, Atsushi, Takenaka, Katsuto, Yasukawa, Masaki, Yamashita, Masakatsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272119/
https://www.ncbi.nlm.nih.gov/pubmed/30302856
http://dx.doi.org/10.1111/cas.13827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272119/
https://www.ncbi.nlm.nih.gov/pubmed/30302856
http://dx.doi.org/10.1111/cas.13827

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