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Thymoquinone inhibits the metastasis of renal cell cancer cells by inducing autophagy via AMPK/mTOR signaling pathway

Thymoquinone (TQ, 2‐methyl‐5‐isopropyl‐1,4‐benzoquinone), a bioactive constituent extracted from the seeds of Nigella sativa, has been proved to exert anti‐tumor efficiency in various cancers. Autophagy is a self‐digestion phenomenon, and its role in tumor formation and progression remains controver...

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Detalles Bibliográficos
Autores principales: Zhang, Yujiao, Fan, Yizeng, Huang, Shangke, Wang, Guanying, Han, Rui, Lei, Fuxi, Luo, Anqi, Jing, Xin, Zhao, Lin, Gu, Shanzhi, Zhao, Xinhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272120/
https://www.ncbi.nlm.nih.gov/pubmed/30259603
http://dx.doi.org/10.1111/cas.13808