Development of Advanced Macrosphelides: Potent Anticancer Agents

Synthetic approaches to macrosphelide derivatives, based on medicinal chemistry, are summarized. This review contains conventional medicinal chemistry approaches, combinatorial chemistry, fluorous tagging techniques and affinity chromatography preparation. In addition, advances in their apoptosis-in...

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Autor principal: Paek, Seung-Mann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272164/
https://www.ncbi.nlm.nih.gov/pubmed/25764486
http://dx.doi.org/10.3390/molecules20034430
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author Paek, Seung-Mann
author_facet Paek, Seung-Mann
author_sort Paek, Seung-Mann
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description Synthetic approaches to macrosphelide derivatives, based on medicinal chemistry, are summarized. This review contains conventional medicinal chemistry approaches, combinatorial chemistry, fluorous tagging techniques and affinity chromatography preparation. In addition, advances in their apoptosis-inducing activities are also included.
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spelling pubmed-62721642018-12-31 Development of Advanced Macrosphelides: Potent Anticancer Agents Paek, Seung-Mann Molecules Review Synthetic approaches to macrosphelide derivatives, based on medicinal chemistry, are summarized. This review contains conventional medicinal chemistry approaches, combinatorial chemistry, fluorous tagging techniques and affinity chromatography preparation. In addition, advances in their apoptosis-inducing activities are also included. MDPI 2015-03-10 /pmc/articles/PMC6272164/ /pubmed/25764486 http://dx.doi.org/10.3390/molecules20034430 Text en © 2015 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Paek, Seung-Mann
Development of Advanced Macrosphelides: Potent Anticancer Agents
title Development of Advanced Macrosphelides: Potent Anticancer Agents
title_full Development of Advanced Macrosphelides: Potent Anticancer Agents
title_fullStr Development of Advanced Macrosphelides: Potent Anticancer Agents
title_full_unstemmed Development of Advanced Macrosphelides: Potent Anticancer Agents
title_short Development of Advanced Macrosphelides: Potent Anticancer Agents
title_sort development of advanced macrosphelides: potent anticancer agents
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272164/
https://www.ncbi.nlm.nih.gov/pubmed/25764486
http://dx.doi.org/10.3390/molecules20034430
work_keys_str_mv AT paekseungmann developmentofadvancedmacrosphelidespotentanticanceragents

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