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Preliminary Biological Evaluation of (18)F-FBEM-Cys-Annexin V a Novel Apoptosis Imaging Agent

A novel annexin V derivative (Cys-Annexin V) with a single cysteine residue at its C-terminal has been developed and successfully labeled site-specifically with (18)F-FBEM. (18)F-FBEM was synthesized by coupling (18)F-fluorobenzoic acid ((18)F-FBA) with N-(2-aminoethyl)maleimide using optimized reac...

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Detalles Bibliográficos
Autores principales:	Lu, Chunxiong, Jiang, Quanfu, Hu, Minjin, Tan, Cheng, Yu, Huixin, Hua, Zichun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272169/ https://www.ncbi.nlm.nih.gov/pubmed/25789822 http://dx.doi.org/10.3390/molecules20034902

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