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Deoxypodophyllotoxin Induces G2/M Cell Cycle Arrest and Apoptosis in SGC-7901 Cells and Inhibits Tumor Growth in Vivo

Deoxypodophyllotoxin (DPT), a natural microtubule destabilizer, was isolated from Anthriscus sylvestris, and a few studies have reported its anti-cancer effect. However, the in vivo antitumor efficacy of DPT is currently indeterminate. In this study, we investigated the anti-gastric cancer effects o...

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Detalles Bibliográficos
Autores principales: Wang, Yu-Rong, Xu, Yuan, Jiang, Zhen-Zhou, Guerram, Mounia, Wang, Bin, Zhu, Xiong, Zhang, Lu-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272175/
https://www.ncbi.nlm.nih.gov/pubmed/25608854
http://dx.doi.org/10.3390/molecules20011661