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Solvent-Free Copper-Catalyzed Azide-Alkyne Cycloaddition under Mechanochemical Activation
The ball-mill-based mechanochemical activation of metallic copper powder facilitates solvent-free alkyne-azide click reactions (CuAAC). All parameters that affect reaction rate (i.e., milling time, revolutions/min, size and milling ball number) have been optimized. This new, efficient, facile and ec...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272186/ https://www.ncbi.nlm.nih.gov/pubmed/25671367 http://dx.doi.org/10.3390/molecules20022837 |