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Solvent-Free Copper-Catalyzed Azide-Alkyne Cycloaddition under Mechanochemical Activation

The ball-mill-based mechanochemical activation of metallic copper powder facilitates solvent-free alkyne-azide click reactions (CuAAC). All parameters that affect reaction rate (i.e., milling time, revolutions/min, size and milling ball number) have been optimized. This new, efficient, facile and ec...

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Detalles Bibliográficos
Autores principales:	Rinaldi, Laura, Martina, Katia, Baricco, Francesca, Rotolo, Laura, Cravotto, Giancarlo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272186/ https://www.ncbi.nlm.nih.gov/pubmed/25671367 http://dx.doi.org/10.3390/molecules20022837

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