Synthesis of Novel bis-1,5-Disubstituted-1H-Tetrazoles by an Efficient Catalyst-Free Ugi-Azide Repetitive Process

A series of five novel bis-1,5-disubstituted-1H-tetrazoles (bis-1,5-DS-1H-T) were quickly prepared by a catalyst-free Ugi-azide repetitive process from easily accessible starting materials in excellent yields, either at room temperature (88%–95%) or using mild MW-heating conditions (80%–91%). These...

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Detalles Bibliográficos
Autores principales: Cárdenas-Galindo, Luís E., Islas-Jácome, Alejandro, Colmenero-Martínez, Karla M., Martínez-Richa, Antonio, Gámez-Montaño, Rocío
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272218/
https://www.ncbi.nlm.nih.gov/pubmed/25608852
http://dx.doi.org/10.3390/molecules20011519
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author Cárdenas-Galindo, Luís E.
Islas-Jácome, Alejandro
Colmenero-Martínez, Karla M.
Martínez-Richa, Antonio
Gámez-Montaño, Rocío
author_facet Cárdenas-Galindo, Luís E.
Islas-Jácome, Alejandro
Colmenero-Martínez, Karla M.
Martínez-Richa, Antonio
Gámez-Montaño, Rocío
author_sort Cárdenas-Galindo, Luís E.
collection PubMed
description A series of five novel bis-1,5-disubstituted-1H-tetrazoles (bis-1,5-DS-1H-T) were quickly prepared by a catalyst-free Ugi-azide repetitive process from easily accessible starting materials in excellent yields, either at room temperature (88%–95%) or using mild MW-heating conditions (80%–91%). These molecules may have a wide range of applications, such as chelating agents, organocatalysts and luminescent materials, and mainly as bioactive compounds.
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spelling pubmed-62722182018-12-28 Synthesis of Novel bis-1,5-Disubstituted-1H-Tetrazoles by an Efficient Catalyst-Free Ugi-Azide Repetitive Process Cárdenas-Galindo, Luís E. Islas-Jácome, Alejandro Colmenero-Martínez, Karla M. Martínez-Richa, Antonio Gámez-Montaño, Rocío Molecules Communication A series of five novel bis-1,5-disubstituted-1H-tetrazoles (bis-1,5-DS-1H-T) were quickly prepared by a catalyst-free Ugi-azide repetitive process from easily accessible starting materials in excellent yields, either at room temperature (88%–95%) or using mild MW-heating conditions (80%–91%). These molecules may have a wide range of applications, such as chelating agents, organocatalysts and luminescent materials, and mainly as bioactive compounds. MDPI 2015-01-16 /pmc/articles/PMC6272218/ /pubmed/25608852 http://dx.doi.org/10.3390/molecules20011519 Text en © 2015 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Cárdenas-Galindo, Luís E.
Islas-Jácome, Alejandro
Colmenero-Martínez, Karla M.
Martínez-Richa, Antonio
Gámez-Montaño, Rocío
Synthesis of Novel bis-1,5-Disubstituted-1H-Tetrazoles by an Efficient Catalyst-Free Ugi-Azide Repetitive Process
title Synthesis of Novel bis-1,5-Disubstituted-1H-Tetrazoles by an Efficient Catalyst-Free Ugi-Azide Repetitive Process
title_full Synthesis of Novel bis-1,5-Disubstituted-1H-Tetrazoles by an Efficient Catalyst-Free Ugi-Azide Repetitive Process
title_fullStr Synthesis of Novel bis-1,5-Disubstituted-1H-Tetrazoles by an Efficient Catalyst-Free Ugi-Azide Repetitive Process
title_full_unstemmed Synthesis of Novel bis-1,5-Disubstituted-1H-Tetrazoles by an Efficient Catalyst-Free Ugi-Azide Repetitive Process
title_short Synthesis of Novel bis-1,5-Disubstituted-1H-Tetrazoles by an Efficient Catalyst-Free Ugi-Azide Repetitive Process
title_sort synthesis of novel bis-1,5-disubstituted-1h-tetrazoles by an efficient catalyst-free ugi-azide repetitive process
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272218/
https://www.ncbi.nlm.nih.gov/pubmed/25608852
http://dx.doi.org/10.3390/molecules20011519
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