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Synthesis and Physicochemical Characterization of the Impurities of Pemetrexed Disodium, an Anticancer Drug

A physicochemical characterization of the process-related impurities associated with the synthesis of pemetrexed disodium was performed. The possibility of pemetrexed impurities forming has been mentioned in literature, but no study on their structure has been published yet. This paper describes the...

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Detalles Bibliográficos
Autores principales: Michalak, Olga, Gruza, Mariusz M., Witkowska, Anna, Bujak, Iwona, Cmoch, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272243/
https://www.ncbi.nlm.nih.gov/pubmed/26035100
http://dx.doi.org/10.3390/molecules200610004