Two New Phenolic Glucosides from Lagerstroemia speciosa

Two new phenolic glucosides, 1-O-benzyl-6-O-E-caffeoyl-β-d-glucopyranoside and 1-O-(7S,8R)-guaiacylglycerol-(6-O-E-caffeoyl)-β-d-glucopyranoside, were isolated from the aerial parts of Lagerstroemia speciosa, along with ten known compounds. The structures of the isolated compounds were determined ba...

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Detalles Bibliográficos
Autores principales: Choi, Janggyoo, Cho, Jae Youl, Choi, Soo Jung, Jeon, Heejin, Kim, Young Dong, Htwe, Khin Myo, Chin, Young Won, Lee, Woo Shin, Kim, Jinwoong, Yoon, Kee Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272251/
https://www.ncbi.nlm.nih.gov/pubmed/25764490
http://dx.doi.org/10.3390/molecules20034483
Descripción
Sumario:Two new phenolic glucosides, 1-O-benzyl-6-O-E-caffeoyl-β-d-glucopyranoside and 1-O-(7S,8R)-guaiacylglycerol-(6-O-E-caffeoyl)-β-d-glucopyranoside, were isolated from the aerial parts of Lagerstroemia speciosa, along with ten known compounds. The structures of the isolated compounds were determined based on 1D- and 2D-NMR, Q-TOF MS and optical rotation spectroscopic data. All of the compounds showed moderate inhibitory activities against nitric oxide production in lipopolysaccharide-treated RAW264.7 cells, with IC(50) values of 69.5–83.3 μM.

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