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Two New Phenolic Glucosides from Lagerstroemia speciosa

Two new phenolic glucosides, 1-O-benzyl-6-O-E-caffeoyl-β-d-glucopyranoside and 1-O-(7S,8R)-guaiacylglycerol-(6-O-E-caffeoyl)-β-d-glucopyranoside, were isolated from the aerial parts of Lagerstroemia speciosa, along with ten known compounds. The structures of the isolated compounds were determined ba...

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Autores principales: Choi, Janggyoo, Cho, Jae Youl, Choi, Soo Jung, Jeon, Heejin, Kim, Young Dong, Htwe, Khin Myo, Chin, Young Won, Lee, Woo Shin, Kim, Jinwoong, Yoon, Kee Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272251/
https://www.ncbi.nlm.nih.gov/pubmed/25764490
http://dx.doi.org/10.3390/molecules20034483
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author Choi, Janggyoo
Cho, Jae Youl
Choi, Soo Jung
Jeon, Heejin
Kim, Young Dong
Htwe, Khin Myo
Chin, Young Won
Lee, Woo Shin
Kim, Jinwoong
Yoon, Kee Dong
author_facet Choi, Janggyoo
Cho, Jae Youl
Choi, Soo Jung
Jeon, Heejin
Kim, Young Dong
Htwe, Khin Myo
Chin, Young Won
Lee, Woo Shin
Kim, Jinwoong
Yoon, Kee Dong
author_sort Choi, Janggyoo
collection PubMed
description Two new phenolic glucosides, 1-O-benzyl-6-O-E-caffeoyl-β-d-glucopyranoside and 1-O-(7S,8R)-guaiacylglycerol-(6-O-E-caffeoyl)-β-d-glucopyranoside, were isolated from the aerial parts of Lagerstroemia speciosa, along with ten known compounds. The structures of the isolated compounds were determined based on 1D- and 2D-NMR, Q-TOF MS and optical rotation spectroscopic data. All of the compounds showed moderate inhibitory activities against nitric oxide production in lipopolysaccharide-treated RAW264.7 cells, with IC(50) values of 69.5–83.3 μM.
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spelling pubmed-62722512018-12-31 Two New Phenolic Glucosides from Lagerstroemia speciosa Choi, Janggyoo Cho, Jae Youl Choi, Soo Jung Jeon, Heejin Kim, Young Dong Htwe, Khin Myo Chin, Young Won Lee, Woo Shin Kim, Jinwoong Yoon, Kee Dong Molecules Article Two new phenolic glucosides, 1-O-benzyl-6-O-E-caffeoyl-β-d-glucopyranoside and 1-O-(7S,8R)-guaiacylglycerol-(6-O-E-caffeoyl)-β-d-glucopyranoside, were isolated from the aerial parts of Lagerstroemia speciosa, along with ten known compounds. The structures of the isolated compounds were determined based on 1D- and 2D-NMR, Q-TOF MS and optical rotation spectroscopic data. All of the compounds showed moderate inhibitory activities against nitric oxide production in lipopolysaccharide-treated RAW264.7 cells, with IC(50) values of 69.5–83.3 μM. MDPI 2015-03-10 /pmc/articles/PMC6272251/ /pubmed/25764490 http://dx.doi.org/10.3390/molecules20034483 Text en © 2015 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Choi, Janggyoo
Cho, Jae Youl
Choi, Soo Jung
Jeon, Heejin
Kim, Young Dong
Htwe, Khin Myo
Chin, Young Won
Lee, Woo Shin
Kim, Jinwoong
Yoon, Kee Dong
Two New Phenolic Glucosides from Lagerstroemia speciosa
title Two New Phenolic Glucosides from Lagerstroemia speciosa
title_full Two New Phenolic Glucosides from Lagerstroemia speciosa
title_fullStr Two New Phenolic Glucosides from Lagerstroemia speciosa
title_full_unstemmed Two New Phenolic Glucosides from Lagerstroemia speciosa
title_short Two New Phenolic Glucosides from Lagerstroemia speciosa
title_sort two new phenolic glucosides from lagerstroemia speciosa
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272251/
https://www.ncbi.nlm.nih.gov/pubmed/25764490
http://dx.doi.org/10.3390/molecules20034483
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