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Antimicrobial and Seasonal Evaluation of the Carvacrol-Chemotype Oil from Lippia origanoides Kunth.

This study evaluated the influence of seasonal variation on the yield and composition of essential oil of Lippia origanoides occurring in the Middle Rio Amazonas, Brazil, and the impact on its antimicrobial potential. The average oil yield was 1.7% ± 0.2% in the rainy season and 1.6% ± 0.3% in the d...

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Autores principales: Sarrazin, Sandra Layse F., da Silva, Leomara Andrade, de Assunção, Ana Paula F., Oliveira, Ricardo B., Calao, Victor Y. P., da Silva, Rodrigo, Stashenko, Elena E., Maia, José Guilherme S., Mourão, Rosa Helena V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272275/
https://www.ncbi.nlm.nih.gov/pubmed/25625681
http://dx.doi.org/10.3390/molecules20021860
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author Sarrazin, Sandra Layse F.
da Silva, Leomara Andrade
de Assunção, Ana Paula F.
Oliveira, Ricardo B.
Calao, Victor Y. P.
da Silva, Rodrigo
Stashenko, Elena E.
Maia, José Guilherme S.
Mourão, Rosa Helena V.
author_facet Sarrazin, Sandra Layse F.
da Silva, Leomara Andrade
de Assunção, Ana Paula F.
Oliveira, Ricardo B.
Calao, Victor Y. P.
da Silva, Rodrigo
Stashenko, Elena E.
Maia, José Guilherme S.
Mourão, Rosa Helena V.
author_sort Sarrazin, Sandra Layse F.
collection PubMed
description This study evaluated the influence of seasonal variation on the yield and composition of essential oil of Lippia origanoides occurring in the Middle Rio Amazonas, Brazil, and the impact on its antimicrobial potential. The average oil yield was 1.7% ± 0.2% in the rainy season and 1.6% ± 0.3% in the dry season. Some correlations with climatic parameters were observed. The major components were carvacrol (rainy, 43.5% ± 1.9%; dry, 41.4% ± 2.04%), thymol (rainy, 10.7% ± 1.1%; dry, 10.6% ± 0.9%), p-cymene (rainy, 9.8% ± 0.7%; dry, 10.0% ± 1.4%) and p-methoxythymol (rainy, 9.6% ± 0.8%; dry, 10.4% ± 1.4%). It was found that the antibacterial activity of L. origanoides against Staphylococcus aureus and Escherichia coli was little influenced by the changes in oil composition due to seasonal variation. Against S. aureus, the oil Minimum Inhibitory Concentration (MIC) value was 1.25 μL/mL over ten months. Against E. coli, the oil MIC values ranged from 0.15 μL/mL to 0.31 μL/mL in different months of the year. The Minimum Bactericidal Concentration (MBC) value was 2.5 μL/mL against S. aureus and 1.25 μL/mL against E. coli. The results suggest that the antimicrobial activity identified in the oil remain unchanged for the full year, allowing its medicinal use without any risk of loss or absence of the active principles of the plant.
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spelling pubmed-62722752018-12-13 Antimicrobial and Seasonal Evaluation of the Carvacrol-Chemotype Oil from Lippia origanoides Kunth. Sarrazin, Sandra Layse F. da Silva, Leomara Andrade de Assunção, Ana Paula F. Oliveira, Ricardo B. Calao, Victor Y. P. da Silva, Rodrigo Stashenko, Elena E. Maia, José Guilherme S. Mourão, Rosa Helena V. Molecules Article This study evaluated the influence of seasonal variation on the yield and composition of essential oil of Lippia origanoides occurring in the Middle Rio Amazonas, Brazil, and the impact on its antimicrobial potential. The average oil yield was 1.7% ± 0.2% in the rainy season and 1.6% ± 0.3% in the dry season. Some correlations with climatic parameters were observed. The major components were carvacrol (rainy, 43.5% ± 1.9%; dry, 41.4% ± 2.04%), thymol (rainy, 10.7% ± 1.1%; dry, 10.6% ± 0.9%), p-cymene (rainy, 9.8% ± 0.7%; dry, 10.0% ± 1.4%) and p-methoxythymol (rainy, 9.6% ± 0.8%; dry, 10.4% ± 1.4%). It was found that the antibacterial activity of L. origanoides against Staphylococcus aureus and Escherichia coli was little influenced by the changes in oil composition due to seasonal variation. Against S. aureus, the oil Minimum Inhibitory Concentration (MIC) value was 1.25 μL/mL over ten months. Against E. coli, the oil MIC values ranged from 0.15 μL/mL to 0.31 μL/mL in different months of the year. The Minimum Bactericidal Concentration (MBC) value was 2.5 μL/mL against S. aureus and 1.25 μL/mL against E. coli. The results suggest that the antimicrobial activity identified in the oil remain unchanged for the full year, allowing its medicinal use without any risk of loss or absence of the active principles of the plant. MDPI 2015-01-23 /pmc/articles/PMC6272275/ /pubmed/25625681 http://dx.doi.org/10.3390/molecules20021860 Text en © 2015 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sarrazin, Sandra Layse F.
da Silva, Leomara Andrade
de Assunção, Ana Paula F.
Oliveira, Ricardo B.
Calao, Victor Y. P.
da Silva, Rodrigo
Stashenko, Elena E.
Maia, José Guilherme S.
Mourão, Rosa Helena V.
Antimicrobial and Seasonal Evaluation of the Carvacrol-Chemotype Oil from Lippia origanoides Kunth.
title Antimicrobial and Seasonal Evaluation of the Carvacrol-Chemotype Oil from Lippia origanoides Kunth.
title_full Antimicrobial and Seasonal Evaluation of the Carvacrol-Chemotype Oil from Lippia origanoides Kunth.
title_fullStr Antimicrobial and Seasonal Evaluation of the Carvacrol-Chemotype Oil from Lippia origanoides Kunth.
title_full_unstemmed Antimicrobial and Seasonal Evaluation of the Carvacrol-Chemotype Oil from Lippia origanoides Kunth.
title_short Antimicrobial and Seasonal Evaluation of the Carvacrol-Chemotype Oil from Lippia origanoides Kunth.
title_sort antimicrobial and seasonal evaluation of the carvacrol-chemotype oil from lippia origanoides kunth.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272275/
https://www.ncbi.nlm.nih.gov/pubmed/25625681
http://dx.doi.org/10.3390/molecules20021860
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