Construction of an Isonucleoside on a 2,6-Dioxobicyclo[3.2.0]-heptane Skeleton

We have built a new isonucleoside derivative on a 2,6-dioxobicyclo[3.2.0]heptane skeleton as a potential anti-HIV agent. To synthesize the target compound, an acetal-protected dihydroxyacetone was first converted to a 2,3-epoxy-tetrahydrofuran derivative. Introduction of an azide group, followed by...

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Detalles Bibliográficos
Autores principales: Yoshimura, Yuichi, Kobayashi, Satoshi, Kaneko, Hitomi, Suzuki, Takeshi, Imamichi, Tomozumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272333/
https://www.ncbi.nlm.nih.gov/pubmed/25774493
http://dx.doi.org/10.3390/molecules20034623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272333/
https://www.ncbi.nlm.nih.gov/pubmed/25774493
http://dx.doi.org/10.3390/molecules20034623

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