Synthesis of a Functionalized Benzofuran as a Synthon for Salvianolic Acid C Analogues as Potential LDL Antioxidants

A palladium mediated synthesis of a common synthon for the syntheses of antioxidant analogues of naturally occurring salvianolic acids is presented. The synthetic route may be used to obtain analogues with a balanced lipophilicity/hydrophilicity which may result in potentially interesting LDL antiox...

Descripción completa

Detalles Bibliográficos
Autores principales: López-Frías, Gabriela, Camacho-Dávila, Alejandro A., Chávez-Flores, David, Zaragoza-Galán, Gerardo, Ramos-Sánchez, Víctor H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272376/
https://www.ncbi.nlm.nih.gov/pubmed/26007172
http://dx.doi.org/10.3390/molecules20058654
Descripción
Sumario:A palladium mediated synthesis of a common synthon for the syntheses of antioxidant analogues of naturally occurring salvianolic acids is presented. The synthetic route may be used to obtain analogues with a balanced lipophilicity/hydrophilicity which may result in potentially interesting LDL antioxidants for the prevention of cardiovascular diseases.

Ejemplares similares