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In Vivo Efficacy and Toxicity Studies of a Novel Antibacterial Agent: 14-O-[(2-Amino-1,3,4-thiadiazol-5-yl)Thioacetyl] Mutilin

A new pleuromutilin derivative with excellent antibacterial activity, 14-O-[(2-amino-1,3,4-thiadiazol-5-yl) thioacetyl] mutilin (ATTM), may serve as a possible lead compound for the development of antibacterial drugs. However, in vivo efficacy and toxicity evaluations of this compound have not been...

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Detalles Bibliográficos
Autores principales:	Zhang, Chao, Yi, Yunpeng, Chen, Jiongran, Xin, Rensheng, Yang, Zhen, Guo, Zhiting, Liang, Jianping, Shang, Ruofeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272395/ https://www.ncbi.nlm.nih.gov/pubmed/25812151 http://dx.doi.org/10.3390/molecules20045299

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