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The Role of Lectin-Carbohydrate Interactions in the Regulation of ER-Associated Protein Degradation
Proteins entering the secretory pathway are translocated across the endoplasmic reticulum (ER) membrane in an unfolded form. In the ER they are restricted to a quality control system that ensures correct folding or eventual degradation of improperly folded polypeptides. Mannose trimming of N-glycans...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272441/ https://www.ncbi.nlm.nih.gov/pubmed/26023941 http://dx.doi.org/10.3390/molecules20069816 |