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The Role of Lectin-Carbohydrate Interactions in the Regulation of ER-Associated Protein Degradation

Proteins entering the secretory pathway are translocated across the endoplasmic reticulum (ER) membrane in an unfolded form. In the ER they are restricted to a quality control system that ensures correct folding or eventual degradation of improperly folded polypeptides. Mannose trimming of N-glycans...

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Detalles Bibliográficos
Autores principales: Słomińska-Wojewódzka, Monika, Sandvig, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272441/
https://www.ncbi.nlm.nih.gov/pubmed/26023941
http://dx.doi.org/10.3390/molecules20069816